Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TGM6 | O95932 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018057 | 0.94 | KMT2A (0.58) | KMT2AMEN1P4HTMALDH1A1MAPT | |
| SCHEMBL9018524 | 0.93 | MAPT (0.50) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL9018256 | 0.92 | KMT2A (0.52) | KMT2AMEN1P4HTMALDH1A1MAPT | |
| SCHEMBL9018480 | 0.91 | MEN1 (0.47) | KMT2AMEN1P4HTMMAPTLMNA | |
| SCHEMBL9018040 | 0.91 | SMN1; SMN2 (0.55) | KMT2AMEN1P4HTMALDH1A1MAPT | |
| SCHEMBL9018146 | 0.91 | CA1 (0.56) | KMT2AMEN1P4HTMALDH1A1MAPT | |
| SCHEMBL9018557 | 0.90 | MAPT (0.51) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL9018127 | 0.90 | PPARA (0.49) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL9018339 | 0.90 | PPARA (0.49) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL9018107 | 0.90 | MAPT (0.51) | KMT2AMEN1MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |