Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348710 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL11023496 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL3161056 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10588845 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL11206299 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL9574615 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10816002 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10813888 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10651393 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10587624 | 1.00 | CHRM2 (0.38) | CHRM2CHRM4CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044010-B1 | NEW PHARMACEUTICAL INTERMEDIATES IN THE SYNTHESIS OF ACE-INIHIBITORS AND THE USE THEREOF | EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDO RESZVENYTARSASAG (HU) | 2014-01-08 | — | — | EP | claimed |
| EP-0344572-A2 | Composition of angiotensin-converting-enzyme inhibitor with calcium chanell modulators and uses thereof as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-06 | — | — | EP | claimed |
| EP-0338508-A2 | Esters from amino-acids, their preparation process, drugs containing same and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | claimed |
| EP-0720988-A1 | Pseudopeptides containing trifluoromethyl substituted 2-azabicyclooctane | BAYER AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0720987-A1 | Acylated pseudopeptides containing trifluoromethyl substituted 2-azabicyclooctane | BAYER AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0297620-B1 | Process for the preparation of byciclic aminocarboxylic acids, intermediates for this process and their use | HOECHST AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| EP-0338508-A2 | Esters from amino-acids, their preparation process, drugs containing same and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0331609-A2 | Angiotensin converting enzyme inhibitors having psychotropic effects | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0326974-A1 | Amino acid amides with a psychotropic activity, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-09 | — | — | EP | disclosed |
| EP-0325160-A2 | Amino-acid glycerides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-26 | — | — | EP | disclosed |
| EP-0317878-A1 | Stabilized pharmaceutical agents, process for preparing them, and stable pharmaceutical preparations | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0297620-A2 | Process for the preparation of byciclic aminocarboxylic acids, intermediates for this process and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | disclosed |