Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30192267 | 0.87 | DRD3 (0.51) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL7451185 | 0.81 | DRD3 (0.55) | DRD3DRD2DRD4HTR1DHTR1B | |
| Cyclopropane Carboxylic Acid SCHEMBL19989732 | 0.81 | DRD3 (0.48) | DRD3DRD2DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7448937 | 0.80 | DRD3 (0.54) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL8691516 | 0.79 | DRD3 (0.46) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL30705735 | 0.79 | DRD3 (0.46) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL8688537 | 0.77 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL30705737 | 0.76 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL9018943 | 0.76 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL9752126 | 0.75 | DRD3 (0.61) | DRD3DRD2DRD4HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712387-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004713-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | THE UPJOHN COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |