Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 15/20 | 0.43 |
| ▸ | SELP | P16109 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019090 | 1.00 | TLR4 (0.43) | TLR4SELPL3MBTL1 | |
| SCHEMBL9019027 | 0.91 | TLR4 (0.36) | TLR4SELPL3MBTL1 | |
| SCHEMBL6800467 | 0.89 | TLR4 (0.46) | TLR4SELPL3MBTL1 | |
| SCHEMBL6800462 | 0.89 | TLR4 (0.46) | TLR4SELPL3MBTL1 | |
| SCHEMBL8435522 | 0.87 | TLR4 (0.44) | TLR4SELPL3MBTL1 | |
| SCHEMBL8433665 | 0.87 | TLR4 (0.44) | TLR4SELPL3MBTL1 | |
| SCHEMBL8434486 | 0.87 | TLR4 (0.44) | TLR4SELPL3MBTL1 | |
| SCHEMBL8431677 | 0.87 | TLR4 (0.44) | TLR4SELPL3MBTL1 | |
| SCHEMBL8577163 | 0.87 | BCHE (0.34) | TLR4SELPL3MBTL1 | |
| SCHEMBL8579402 | 0.87 | BCHE (0.34) | TLR4SELPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |