Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 9/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795186 | 0.83 | GSR (0.51) | GSRBCHECA2ALDH1A1MAPT | |
| SCHEMBL9795429 | 0.80 | GSR (0.45) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9500143 | 0.80 | GSR (0.45) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9795344 | 0.79 | GSR (0.44) | GSRBCHECA2ALDH1A1MAPT | |
| SCHEMBL29315346 | 0.79 | KMT2A (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9501683 | 0.77 | GSR (0.45) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9795129 | 0.77 | GSR (0.45) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9795375 | 0.77 | GSR (0.42) | GSRBCHEMAPT | |
| SCHEMBL9795291 | 0.77 | GSR (0.42) | GSRBCHECA2ALDH1A1MAPT | |
| SCHEMBL9497885 | 0.77 | GSR (0.42) | GSRBCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-B1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-12 | — | — | EP | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |