Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.50 |
| ▸ | PTGIR | P43119 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622630 | 1.00 | PTGDR2 (0.52) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL7622615 | 1.00 | PTGDR2 (0.52) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL7614725 | 0.97 | PTGER2 (0.49) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL7614717 | 0.97 | PTGER2 (0.49) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL8594912 | 0.97 | PTGER2 (0.49) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL12455951 | 0.96 | PTGER2 (0.49) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL15779590 | 0.96 | PTGER2 (0.49) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL9127033 | 0.93 | PTGDR2 (0.52) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL16504094 | 0.93 | PTGDR2 (0.52) | PTGDR2PTGER2PTGER4PTGIRTSHR | |
| SCHEMBL9127017 | 0.93 | PTGDR2 (0.52) | PTGDR2PTGER2PTGER4PTGIRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503887-B1 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0467564-B1 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0503887-A2 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0467564-A2 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |