Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.39 |
| ▸ | EIF4E | P06730 | 3/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021807 | 0.95 | HPRT1 (0.40) | HPRT1EIF4EBACE1 | |
| SCHEMBL9020094 | 0.94 | HPRT1 (0.39) | HPRT1EIF4EBACE1 | |
| SCHEMBL9020254 | 0.88 | HPRT1 (0.39) | HPRT1EIF4E | |
| SCHEMBL9020199 | 0.85 | HPRT1 (0.41) | HPRT1 | |
| SCHEMBL9020007 | 0.84 | HPRT1 (0.37) | HPRT1EIF4E | |
| SCHEMBL9020717 | 0.84 | HPRT1 (0.40) | HPRT1 | |
| SCHEMBL9020182 | 0.84 | HPRT1 (0.40) | HPRT1 | |
| SCHEMBL9020167 | 0.84 | HPRT1 (0.37) | HPRT1EIF4E | |
| SCHEMBL9020330 | 0.83 | HPRT1 (0.40) | HPRT1EIF4E | |
| SCHEMBL9020711 | 0.83 | HPRT1 (0.38) | HPRT1EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458312-B1 | Novel cyclobutane derivatives | NIPPON KAYAKU KK (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5324730-A | Viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |