Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020330 | 0.95 | HPRT1 (0.40) | HPRT1ALDH1A1EIF4ENOS1P2RY2 | |
| SCHEMBL9020254 | 0.93 | HPRT1 (0.39) | HPRT1ALDH1A1IRAK4EIF4ENOS1 | |
| SCHEMBL9020359 | 0.93 | HPRT1 (0.38) | HPRT1EIF4E | |
| SCHEMBL9020473 | 0.92 | HPRT1 (0.38) | HPRT1P2RY14 | |
| SCHEMBL9020219 | 0.92 | HPRT1 (0.38) | HPRT1 | |
| SCHEMBL9020310 | 0.92 | HPRT1 (0.38) | HPRT1EIF4EP2RY2 | |
| SCHEMBL9020093 | 0.91 | HPRT1 (0.36) | HPRT1IRAK4 | |
| SCHEMBL9020065 | 0.91 | HPRT1 (0.36) | HPRT1EIF4EP2RY2P2RY6P2RY14 | |
| SCHEMBL9020309 | 0.90 | HPRT1 (0.37) | HPRT1IRAK4EIF4E | |
| SCHEMBL9020288 | 0.89 | HPRT1 (0.37) | HPRT1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458312-B1 | Novel cyclobutane derivatives | NIPPON KAYAKU KK (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5324730-A | Viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |