Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13243495 | 0.87 | ACACB (0.60) | ACACBNPC1RAB9A | |
| SCHEMBL9020783 | 0.85 | ACACB (0.59) | ACACBNPC1RAB9A | |
| SCHEMBL25596399 | 0.85 | ACACB (0.59) | ACACBNPC1RAB9A | |
| SCHEMBL165893 | 0.83 | ACACB (0.58) | ACACBNPC1RAB9A | |
| SCHEMBL10948969 | 0.83 | NPC1 (0.71) | ACACBNPC1RAB9A | |
| SCHEMBL15116559 | 0.83 | NPC1 (0.71) | ACACBNPC1RAB9A | |
| SCHEMBL255697 | 0.80 | ACACB (0.65) | ACACB | |
| SCHEMBL20943574 | 0.78 | ACACB (0.66) | ACACBNPC1RAB9A | |
| SCHEMBL17931614 | 0.78 | ACACB (0.66) | ACACBNPC1RAB9A | |
| SCHEMBL12001475 | 0.76 | ACACB (0.81) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |