⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797832 | 0.73 | — | — | |
| SCHEMBL902094 | 0.71 | — | — | |
| SCHEMBL9381557 | 0.70 | — | — | |
| SCHEMBL275382 | 0.55 | — | — | |
| SCHEMBL3943291 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL3861041 | 0.45 | — | — | |
| SCHEMBL73936 | 0.37 | — | — | |
| SCHEMBL26660960 | 0.33 | — | — | |
| SCHEMBL1465460 | 0.31 | — | — | |
| SCHEMBL890278 | 0.29 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627626-B2 | Antiinflammation agents and antiarthritic agents colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals. | PFIZER INC. | 2003-09-30 | — | — | US | claimed |
| US-20030144279-A1 | 5-Heterocyclo-pyrazoles | MINICH MARTHA L (US) | 2003-07-31 | — | — | US | claimed |
| WO-2003037352-A1 | 1-PHENYL-5-N-HETEROCYCLYL-PYRAZOLES AS CYCLOOXYGENASE INHIBITORS FOR THE TREATMENT OF INFLAMMATION ASSOCIATED DISORDERS | PFIZER PRODUCTS INC. (US) | 2003-05-08 | — | — | WO | claimed |
| EP-1308161-A1 | 5-N-heterocyclyl-1-(4-sulfonyl-phenyl)-1H-pyrazole derivatives with cyclooxygenase 2 (COX-2) inhibiting activity for the treatment of inflammatory diseases | Pfizer Products Inc. (US) | 2003-05-07 | — | — | EP | claimed |
| WO-2012042227-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS | PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) | 2012-04-05 | — | — | WO | disclosed |
| EP-1308161-B1 | 5-N-heterocyclyl-1-(4-sulfonyl-phenyl)-1H-pyrazole derivatives with cyclooxygenase 2 (COX-2) inhibiting activity for the treatment of inflammatory diseases | PFIZER PROD INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-6627626-B2 | Antiinflammation agents and antiarthritic agents colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals. | PFIZER INC. | 2003-09-30 | — | — | US | disclosed |
| US-20030144279-A1 | 5-Heterocyclo-pyrazoles | MINICH MARTHA L (US) | 2003-07-31 | — | — | US | disclosed |
| WO-2003037352-A1 | 1-PHENYL-5-N-HETEROCYCLYL-PYRAZOLES AS CYCLOOXYGENASE INHIBITORS FOR THE TREATMENT OF INFLAMMATION ASSOCIATED DISORDERS | PFIZER PRODUCTS INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| EP-1308161-A1 | 5-N-heterocyclyl-1-(4-sulfonyl-phenyl)-1H-pyrazole derivatives with cyclooxygenase 2 (COX-2) inhibiting activity for the treatment of inflammatory diseases | Pfizer Products Inc. (US) | 2003-05-07 | — | — | EP | disclosed |