Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 19/20 | 0.73 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022335 | 1.00 | SRD5A1 (0.73) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9021989 | 0.97 | SRD5A1 (0.77) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9021996 | 0.97 | SRD5A1 (0.77) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022092 | 0.94 | SRD5A1 (0.76) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022095 | 0.94 | SRD5A1 (0.76) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022684 | 0.91 | SRD5A1 (0.72) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022689 | 0.91 | SRD5A1 (0.72) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022078 | 0.91 | SRD5A1 (0.72) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9022071 | 0.91 | SRD5A1 (0.72) | SRD5A1SRD5A2ABCC4ABCB11LMNA | |
| SCHEMBL9021908 | 0.89 | SRD5A1 (0.68) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484094-B1 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO CO (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5302621-A | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0484094-A2 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | Sankyo Company Limited (JP) | 1992-05-06 | — | — | EP | disclosed |