Sugi Predict

Sugi Predict / Compounds / SCHEMBL9022536

SCHEMBL9022536

SCHEMBL9022536

C[C@]12C=CC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](OC(=O)NC(c3ccccc3)c3ccccc3)CC[C@@H]12

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SRD5A1 P18405 15/20 0.61
▸ SRD5A2 P31213 8/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022097 0.96 SRD5A1 (0.58) SRD5A1SRD5A2
SCHEMBL9022262 0.92 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL9022133 0.89 SRD5A1 (0.56) SRD5A1SRD5A2
SCHEMBL9022589 0.86 SRD5A1 (0.54) SRD5A1SRD5A2
SCHEMBL9022092 0.86 SRD5A1 (0.76) SRD5A1SRD5A2
SCHEMBL9022095 0.86 SRD5A1 (0.76) SRD5A1SRD5A2
SCHEMBL9022917 0.84 SRD5A2 (0.58) SRD5A1SRD5A2
SCHEMBL9022341 0.84 SRD5A1 (0.64) SRD5A1SRD5A2
SCHEMBL9022413 0.84 SRD5A1 (0.64) SRD5A1SRD5A2
SCHEMBL4369408 0.83 SRD5A1 (0.63) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 — — EP claimed