SCHEMBL9022608

SCHEMBL9022608

CC(NC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.57
SRD5A1 P18405 5/20 0.57
AR P10275 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022557 0.93 SRD5A2 (0.57) SRD5A2SRD5A1AR
SCHEMBL9022150 0.85 SRD5A2 (0.73) SRD5A2SRD5A1AR
SCHEMBL9022155 0.85 SRD5A2 (0.73) SRD5A2SRD5A1AR
SCHEMBL9022341 0.84 SRD5A1 (0.64) SRD5A2SRD5A1
SCHEMBL9022623 0.84 SRD5A2 (0.49) SRD5A2SRD5A1AR
SCHEMBL9022917 0.83 SRD5A2 (0.58) SRD5A2SRD5A1AR
SCHEMBL9022673 0.83 SRD5A2 (0.50) SRD5A2SRD5A1AR
SCHEMBL9023070 0.83 SRD5A2 (0.50) SRD5A2SRD5A1AR
SCHEMBL9022691 0.82 SRD5A1 (0.54) SRD5A2SRD5A1
SCHEMBL4379567 0.81 SRD5A2 (0.60) SRD5A2SRD5A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484094-B1 Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use SANKYO CO (JP) 1996-06-26 EP claimed