SCHEMBL9022677

SCHEMBL9022677

Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C)c2cc1N

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.69
KMT2A Q03164 7/20 0.69
MAPT P10636 3/20 0.69
RECQL P46063 3/20 0.69
TDP2 O95551 2/20 0.69
NGF P01138 1/20 0.69
NTRK1 P04629 1/20 0.69
BLM P54132 1/20 0.69
USP2 O75604 5/20 0.50
KDM4E B2RXH2 4/20 0.50
HTT P42858 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
RXFP1 Q9HBX9 2/20 0.50
IDO1 P14902 1/20 0.50
HAT1 O14929 4/20 0.46
RBBP7 Q16576 4/20 0.46
HPGD P15428 3/20 0.46
CASP1 P29466 2/20 0.46
BRCA1 P38398 2/20 0.46
CASP7 P55210 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lumiflavin SCHEMBL29516802 0.89 MEN1 (0.76) MEN1KMT2AMAPTRECQLTDP2
Lumiflavin SCHEMBL193713 0.89 MEN1 (0.76) MEN1KMT2AMAPTRECQLTDP2
Lumiflavin SCHEMBL6365933 0.87 MEN1 (0.74) MEN1KMT2AMAPTRECQLTDP2
Lumiflavin SCHEMBL6373617 0.86 MEN1 (0.72) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL864918 0.84 MEN1 (0.69) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL27872115 0.82 MEN1 (0.55) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL29375964 0.82 MEN1 (1.00) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL15683182 0.82 MEN1 (1.00) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL16557144 0.82 MEN1 (0.66) MEN1KMT2AMAPTRECQLTDP2
SCHEMBL10285873 0.82 MEN1 (0.66) MEN1KMT2AMAPTRECQLTDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739208-A1 FLAVIN DERIVATIVES AS ANTI-VIRAL AGENTS RADOPATH LIMITED (GB) 1996-10-30 EP disclosed
WO-1995011028-A1 FLAVIN DERIVATIVES AS ANTI-VIRAL AGENTS RADOPATH LIMITED (GB) 1995-04-27 WO disclosed