Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 15/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023019 | 1.00 | SRD5A2 (0.48) | SRD5A2SRD5A1AR | |
| SCHEMBL9022106 | 0.92 | SRD5A1 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL9022101 | 0.92 | SRD5A1 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL9022089 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022200 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022882 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022887 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022194 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022087 | 0.89 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL9022514 | 0.85 | SRD5A2 (0.47) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484094-B1 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO CO (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5302621-A | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0484094-A2 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | Sankyo Company Limited (JP) | 1992-05-06 | — | — | EP | disclosed |