Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.59 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 15/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023306 | 1.00 | KCNH2 (0.59) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9023318 | 1.00 | KCNH2 (0.59) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8436499 | 0.89 | KCNH2 (0.58) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9023598 | 0.86 | KCNH2 (0.56) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9023210 | 0.84 | KCNH2 (0.67) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8437288 | 0.84 | KCNH2 (0.67) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9022918 | 0.84 | KCNH2 (0.67) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9023057 | 0.84 | KCNH2 (0.53) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9394230 | 0.84 | MEN1 (0.48) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10577825 | 0.84 | CACNA1F (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641793-B1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5547962-A | QUINOLONE ANTIBIOTICS | HORURIKU SEIYAKU CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0641793-A1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |