Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20967986 | 1.00 | CHRM2 (0.54) | CHRM2CHRM4CHRM5LMNAKMT2A | |
| SCHEMBL8120312 | 1.00 | CHRM2 (0.54) | CHRM2CHRM4CHRM5LMNAKMT2A | |
| SCHEMBL21772974 | 0.93 | CHRM2 (0.58) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| SCHEMBL21777244 | 0.93 | CHRM2 (0.58) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| SCHEMBL168286 | 0.93 | CHRM2 (0.58) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| SCHEMBL15021133 | 0.93 | CHRM2 (0.58) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| SCHEMBL168287 | 0.93 | CHRM2 (0.58) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4995917 | 0.91 | CHRM2 (0.61) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4020237 | 0.90 | CHRM2 (0.59) | CHRM2CHRM4CHRM5KMT2AL3MBTL1 | |
| SCHEMBL21266577 | 0.87 | CHRM2 (0.65) | CHRM2CHRM4CHRM5LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640601-B1 | BENZAMIDE DERIVATIVE | HOKURIKU PHARMACEUTICAL (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5500422-A | FOR TREATING GASTROINTESTINAL DISEASES | HOKURIKU SEIYAKU CO. LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| US-5395832-A | Gastrointestinal disorders | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0640601-A1 | BENZAMIDE DERIVATIVE | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |