SCHEMBL902356

SCHEMBL902356

C#CCNCCCCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333040 0.97 SAT1 (0.60)
SCHEMBL332496 0.97 SAT1 (0.60)
Hydrochloric Acid SCHEMBL8619211 0.97 SAT1 (0.60)
SCHEMBL332482 0.97 SAT1 (0.60)
SCHEMBL9348906 0.97 SAT1 (0.60)
Ammonia Solution, Strong SCHEMBL29003562 0.97 SAT1 (0.60)
SCHEMBL6832121 0.97 SAT1 (0.60)
SCHEMBL333304 0.97 SAT1 (0.60)
SCHEMBL333465 0.97 SAT1 (0.60)
SCHEMBL4424094 0.97 SAT1 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109053618-A Preparation method of oxazole derivative 青岛科技大学 2018-12-21 CN claimed
EP-0996612-B1 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS UNIV SASKATCHEWAN (CA) 2003-04-09 EP claimed
US-6251950-B1 ADMINISTERING TO THE PATIENT AN ALIPHATIC-PROPARGYLAMINE OR SALT FOR THE TREATMENT OF ACUTE AND CHRONIC DISEASES IN WHICH CELL DEATH OCCURS BY APOPTOSIS OR FOR THE TREATMENT OF PREMATURE DEGENERATION OF CELLS IN MAMMALS UNIVERSITY OF SASKATCHEWAN (CA) 2001-06-26 US claimed
EP-0996612-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS University of Saskatchewan Technologies Inc. (CA) 2000-05-03 EP claimed
WO-1999003817-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) 1999-01-28 WO claimed
CN-106146334-B 2,3- diaryl -2- alkynes propionamido- -3- arylamino methyl propionate derivative and its preparation method and application 华东师范大学 2019-01-18 CN disclosed
WO-2012041934-A1 POLYSUBSTITUTED 2-AMINOIMIDAZOLES FOR CONTROLLING BIOFILMS AND PROCESS FOR THEIR PRODUCTION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2012-04-05 WO disclosed
EP-2281818-A1 Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2011-02-09 EP disclosed
US-20080261947-A1 FUSED PYRIDAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. 2008-10-23 US disclosed
US-20080261947-A1 FUSED PYRIDAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. 2008-10-23 US disclosed
US-7402580-B2 Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-7402580-B2 Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-22 US disclosed
EP-0819000-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 2001-04-11 EP disclosed
EP-0996612-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS University of Saskatchewan Technologies Inc. (CA) 2000-05-03 EP disclosed
WO-1999003817-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) 1999-01-28 WO disclosed
US-5840979-A USEFUL IN THE TREATMENT AND PREVENTION OF DISEASES IN WHICH CELL DEATH OCCURS BY APOPTOSIS UNIVERSITY OF SASKATCHEWAN (CA) 1998-11-24 US disclosed
EP-0819000-A1 NODULISPORIC ACID DERIVATIVES Merck & Co., Inc. (US) 1998-01-21 EP disclosed
US-4452745-A ANTIARRHYTHMIA AGENTS ELI LILLY AND COMPANY (US) 1984-06-05 US disclosed
US-4382093-A 9-Aminoalkylfluorenes ELI LILLY AND COMPANY (US) 1983-05-03 US disclosed
US-4277495-A FLUORENE 9-AMINOALKYL-9-CARBOXYLIC ACIDS OR ESTERS ELI LILLY AND COMPANY (US) 1981-07-07 US disclosed