Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023644 | 1.00 | KCNH2 (0.58) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL10685966 | 0.90 | KCNH2 (0.58) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8110519 | 0.89 | KCNH2 (0.73) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8925391 | 0.86 | KCNH2 (0.57) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL9457034 | 0.86 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL9457207 | 0.86 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8925462 | 0.86 | KCNH2 (0.57) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8573733 | 0.86 | KCNH2 (0.56) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8566245 | 0.86 | KCNH2 (0.56) | KCNH2HRH3ALDH1A1POLBCHRM2 | |
| SCHEMBL8925399 | 0.86 | KCNH2 (0.57) | KCNH2HRH3ALDH1A1POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641793-B1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5547962-A | QUINOLONE ANTIBIOTICS | HORURIKU SEIYAKU CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0641793-A1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |