Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902366 | 1.00 | PTGS1 (0.36) | PTGS1SLC7A11 | |
| SCHEMBL1509586 | 0.79 | KMT2A (0.42) | — | |
| SCHEMBL1509587 | 0.79 | KMT2A (0.42) | — | |
| SCHEMBL4952914 | 0.79 | GRM8 (0.43) | — | |
| SCHEMBL4952904 | 0.79 | GRM8 (0.43) | — | |
| Hydrochloric Acid SCHEMBL3676282 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL6753730 | 0.78 | GSR (0.43) | — | |
| SCHEMBL10411479 | 0.74 | ALPI (0.49) | PTGS1 | |
| SCHEMBL10411481 | 0.74 | ALPI (0.49) | PTGS1 | |
| SCHEMBL355916 | 0.74 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621535-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | Philogen S.p.A. (IT) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041451-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | PHILOGEN S.P.A. (IT) | 2012-04-05 | — | — | WO | disclosed |