Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 8/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006279 | 1.00 | PTGDR (0.48) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9006184 | 0.97 | PTGDR (0.47) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9025339 | 0.97 | PTGDR (0.47) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9024374 | 0.97 | PTGDR (0.47) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9006079 | 0.97 | PTGDR (0.47) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9006113 | 0.97 | PTGDR (0.49) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9024290 | 0.97 | PTGDR (0.49) | PTGDRTBXA2RTBXAS1HTTPTGIR | |
| SCHEMBL9023689 | 0.92 | TBXA2R (0.44) | PTGDRTBXA2RTBXAS1HTT | |
| SCHEMBL9006228 | 0.92 | TBXA2R (0.44) | PTGDRTBXA2RTBXAS1HTT | |
| SCHEMBL9025167 | 0.91 | TBXA2R (0.48) | PTGDRTBXA2RTBXAS1HTTPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367130-B1 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5264453-A | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5130323-A | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |