Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024753 | 1.00 | TACR1 (0.71) | TACR1 | |
| SCHEMBL9025631 | 0.89 | TACR1 (0.67) | TACR1 | |
| SCHEMBL9024898 | 0.89 | TACR1 (0.69) | TACR1 | |
| Hydrochloric Acid SCHEMBL9024799 | 0.88 | TACR1 (0.66) | TACR1 | |
| Hydrochloric Acid SCHEMBL9024287 | 0.88 | TACR1 (0.68) | TACR1 | |
| SCHEMBL9024498 | 0.87 | TACR1 (0.70) | TACR1 | |
| SCHEMBL9024496 | 0.87 | TACR1 (0.70) | TACR1 | |
| SCHEMBL8545494 | 0.86 | TACR1 (0.64) | TACR1 | |
| SCHEMBL19202253 | 0.85 | TACR1 (0.76) | TACR1 | |
| Hydrochloric Acid SCHEMBL8539710 | 0.85 | TACR1 (0.63) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600952-B1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME (GB) | 1996-04-17 | — | — | EP | claimed |
| EP-0600952-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | MERCK SHARP & DOHME (GB) | 1994-06-15 | — | — | EP | claimed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | claimed |
| EP-0528495-A1 | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them | MERCK SHARP & DOHME LTD. (GB) | 1993-02-24 | — | — | EP | claimed |