Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023464 | 0.95 | HTR2C (0.57) | HTR2CHTR2ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL9023876 | 0.94 | HTR2C (0.56) | HTR2CHTR2ADRD2HTR7 | |
| Salicylic Acid SCHEMBL9023656 | 0.93 | HTR2C (0.55) | HTR2CHTR2ADRD2HTR7 | |
| SCHEMBL9024751 | 0.92 | HTR2C (0.54) | HTR2CHTR2ADRD2HTR7 | |
| SCHEMBL9025797 | 0.90 | HTR2C (0.61) | HTR2CHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL9024762 | 0.89 | HTR2C (0.60) | HTR2CHTR2ADRD2 | |
| SCHEMBL9023838 | 0.85 | HTR2C (0.55) | HTR2CHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL9023939 | 0.84 | HTR2C (0.54) | HTR2CHTR2ADRD2 | |
| SCHEMBL9445199 | 0.84 | HTR2C (0.57) | HTR2CHTR2ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL9024725 | 0.83 | HTR2C (0.56) | HTR2CHTR2ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| EP-0474012-B1 | 6,7-Dihydro-3-phenyl-1,2-benzisoxazol-4(5H)-ones and -ols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-11-27 | — | — | EP | disclosed |
| US-5256672-A | Antipsychotic, analgesic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-10-26 | — | — | US | disclosed |
| US-5180834-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-19 | — | — | US | disclosed |
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0474012-A1 | 6,7-Dihydro-3-phenyl-1,2-benzisoxazol-4(5H)-ones and -ols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-03-11 | — | — | EP | disclosed |