Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025058 | 1.00 | TACR1 (0.82) | TACR1 | |
| SCHEMBL9025177 | 0.95 | TACR1 (0.83) | TACR1 | |
| SCHEMBL9025277 | 0.95 | TACR1 (0.83) | TACR1 | |
| SCHEMBL9024620 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9024608 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8539295 | 0.89 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8541443 | 0.83 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8541022 | 0.83 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8541026 | 0.83 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9026103 | 0.83 | TACR1 (0.72) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600952-B1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME (GB) | 1996-04-17 | — | — | EP | claimed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | disclosed |