Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930460 | 1.00 | TYMP (0.40) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL31138990 | 0.97 | TYMP (0.42) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL5930041 | 0.90 | TYMP (0.46) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL22879082 | 0.90 | TYMP (0.46) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL5930032 | 0.90 | TYMP (0.46) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL6650591 | 0.85 | TYMP (0.39) | TYMPKIF11MEN1KMT2A | |
| SCHEMBL19297563 | 0.85 | TYMP (0.39) | TYMPKIF11MEN1KMT2A | |
| SCHEMBL19297527 | 0.85 | TYMP (0.39) | TYMPKIF11MEN1KMT2A | |
| SCHEMBL19297648 | 0.83 | MEN1 (0.38) | TYMPKIF11MEN1KMT2ASLC5A2 | |
| SCHEMBL19297661 | 0.83 | MEN1 (0.38) | TYMPKIF11MEN1KMT2ASLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464769-B1 | Purinyl and pyrimidinyl tetrahydrofurans | SQUIBB & SONS INC (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5272152-A | Purinyl and pyrimidinyl tetrahydrofurans | E. R. SQUIBB & SONS, INC. (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0464769-A2 | Purinyl and pyrimidinyl tetrahydrofurans | E.R. SQUIBB & SONS, INC. (US) | 1992-01-08 | — | — | EP | disclosed |