Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025626 | 1.00 | MAPT (0.41) | MAPTTSHRMAPK1STAT3SMN1; SMN2 | |
| SCHEMBL9025623 | 0.83 | CACNA1C (0.42) | SMN1; SMN2ALDH1A1LMNACACNA1CKDM4E | |
| SCHEMBL9025620 | 0.83 | CACNA1C (0.42) | SMN1; SMN2ALDH1A1LMNACACNA1CKDM4E | |
| SCHEMBL9024866 | 0.83 | MEN1 (0.41) | MAPTTSHRMAPK1STAT3SMN1; SMN2 | |
| SCHEMBL9025659 | 0.77 | ESR1 (0.43) | MAPTSMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL9025666 | 0.77 | ESR1 (0.43) | MAPTSMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL21081297 | 0.77 | CACNA1C (0.46) | SMN1; SMN2POLBALDH1A1HPGDLMNA | |
| SCHEMBL9025908 | 0.75 | CACNA1C (0.42) | LMNACACNA1CKDM4EMEN1KMT2A | |
| SCHEMBL9025899 | 0.75 | CACNA1C (0.42) | LMNACACNA1CKDM4EMEN1KMT2A | |
| SCHEMBL9026409 | 0.75 | CACNA1C (0.42) | LMNACACNA1CKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704446-A1 | NOVEL BETA-LACTAM COMPOUND AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-03 | — | — | EP | disclosed |