Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.80 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571845 | 1.00 | HIF1A (0.80) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL4564428 | 0.91 | HIF1A (0.71) | HIF1AALDH1A1OPRL1HPGDHTT | |
| SCHEMBL8623305 | 0.89 | HIF1A (0.65) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL8623308 | 0.89 | HIF1A (0.65) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL9450116 | 0.89 | HIF1A (0.69) | HIF1AALDH1A1SMN1; SMN2PTPRCPTPN1 | |
| SCHEMBL22414343 | 0.89 | HIF1A (1.00) | HIF1AMAPK10KDM4ESMN1; SMN2NR4A2 | |
| SCHEMBL30746040 | 0.89 | HIF1A (0.69) | HIF1AALDH1A1SMN1; SMN2PTPRCPTPN1 | |
| SCHEMBL13772688 | 0.88 | HIF1A (0.63) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL8369852 | 0.87 | HIF1A (0.63) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL8369854 | 0.87 | HIF1A (0.63) | HIF1ACAPN1TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493711-B1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF AG (DE) | 1996-09-25 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |