Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | CTSH | P09668 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025867 | 0.93 | MAPT (0.31) | MAPTL3MBTL1 | |
| SCHEMBL8785007 | 0.79 | TSHR (0.39) | MAPT | |
| SCHEMBL5370039 | 0.78 | ACACB (0.36) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL2990263 | 0.78 | ACACB (0.36) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL2986183 | 0.78 | ACACB (0.36) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL10321962 | 0.78 | ACACB (0.36) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL2984985 | 0.74 | HPGD (0.41) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL2991371 | 0.74 | HPGD (0.41) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL5513339 | 0.74 | TP53 (0.39) | EPHX2CTSLCTSBCTSHCTSK | |
| SCHEMBL10321883 | 0.74 | HPGD (0.41) | EPHX2CTSLCTSBCTSHCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719774-A1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5310940-A | Sulfiding, cyclization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5221749-A | Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5093504-A | PRODUCTION OF THIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS, TETRAHYDROTHIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS AND DIBENZOXAZOLYLTHIOPHENES | SUMITOMO SEIKA CHEMICALS, CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |