Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612418 | 0.84 | HPGD (0.54) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL13602488 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9026811 | 0.84 | POLB (0.46) | SMN1; SMN2HPGDMAPTHSD17B10L3MBTL1 | |
| SCHEMBL9026256 | 0.82 | MAPK9 (0.35) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9026635 | 0.80 | CYP2A6 (0.44) | SMN1; SMN2MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL13784459 | 0.77 | BRAF (0.52) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9026693 | 0.74 | MAPT (0.43) | SMN1; SMN2HPGDMAPTHSD17B10L3MBTL1 | |
| SCHEMBL5612412 | 0.73 | MAPT (0.51) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL27861242 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL8280284 | 0.71 | SMO (0.54) | SMN1; SMN2HPGDMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366329-B1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL IND LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5220028-A | Halogeno-4-methylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0366329-A1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |