⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026479 | 1.00 | — | — | |
| SCHEMBL9026485 | 1.00 | — | — | |
| SCHEMBL9027411 | 0.92 | — | — | |
| SCHEMBL9027417 | 0.92 | — | — | |
| SCHEMBL9029055 | 0.92 | — | — | |
| SCHEMBL9026625 | 0.92 | — | — | |
| SCHEMBL9026617 | 0.92 | — | — | |
| SCHEMBL9027054 | 0.91 | HMGCR (0.40) | — | |
| SCHEMBL9027154 | 0.91 | — | — | |
| SCHEMBL9027167 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3258778-A | — | — | None | — | — | JP | disclosed |
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| JP-H03258778-A | 4-HYDROXYTETERAHYDROPYRAN-2-ONE DERIVATIVE | FUJIREBIO INC | 1991-11-19 | — | — | JP | disclosed |