Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027840 | 0.86 | KMT2A (0.40) | GPR84MEN1KMT2ANMBRNR3C1 | |
| SCHEMBL9027253 | 0.86 | KMT2A (0.40) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL9026078 | 0.85 | KMT2A (0.40) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL9026147 | 0.85 | KMT2A (0.40) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL9026638 | 0.84 | KMT2A (0.39) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL9027273 | 0.83 | KMT2A (0.38) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL9026084 | 0.82 | KCNA5 (0.38) | GPR84MEN1KMT2ANMBRECE1 | |
| SCHEMBL27257402 | 0.81 | MEN1 (0.41) | GPR84MEN1KMT2ANMBRNR3C1 | |
| SCHEMBL9026748 | 0.81 | CA12 (0.35) | L3MBTL1MMP2 | |
| SCHEMBL9026548 | 0.81 | HPGD (0.37) | L3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |