⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027160 | 1.00 | — | — | |
| SCHEMBL9027172 | 1.00 | — | — | |
| SCHEMBL9027153 | 1.00 | — | — | |
| SCHEMBL9028809 | 0.92 | — | — | |
| SCHEMBL9028821 | 0.92 | — | — | |
| SCHEMBL9028798 | 0.92 | — | — | |
| SCHEMBL9028801 | 0.92 | — | — | |
| SCHEMBL9084524 | 0.79 | HMGCR (0.49) | — | |
| SCHEMBL9084517 | 0.79 | HMGCR (0.49) | — | |
| SCHEMBL9026485 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |