Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028345 | 0.90 | KDM4E (0.42) | KDM4EL3MBTL1KMT2AALDH1A1HRH3 | |
| SCHEMBL9028327 | 0.90 | TACR1 (0.41) | HRH3TRPV4 | |
| SCHEMBL9027244 | 0.83 | KMT2A (0.47) | KDM4EL3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL8883877 | 0.82 | KMT2A (0.46) | KDM4EL3MBTL1KMT2AALDH1A1HRH3 | |
| SCHEMBL8883870 | 0.82 | KMT2A (0.46) | KDM4EL3MBTL1KMT2AALDH1A1HRH3 | |
| SCHEMBL9028740 | 0.80 | KDM4E (0.39) | KDM4EL3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL9028179 | 0.80 | TACR1 (0.41) | HRH3 | |
| SCHEMBL9028133 | 0.78 | TACR1 (0.41) | KDM4EL3MBTL1HRH3 | |
| SCHEMBL9028322 | 0.77 | TACR1 (0.49) | — | |
| SCHEMBL9028111 | 0.77 | TACR1 (0.42) | KDM4EL3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563133-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |