⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902586 | 0.75 | — | — | |
| SCHEMBL10351000 | 0.71 | — | — | |
| SCHEMBL7229293 | 0.71 | — | — | |
| SCHEMBL10638108 | 0.67 | — | — | |
| SCHEMBL3107554 | 0.67 | — | — | |
| SCHEMBL1758111 | 0.65 | — | — | |
| SCHEMBL7229719 | 0.65 | — | — | |
| SCHEMBL7228703 | 0.65 | — | — | |
| SCHEMBL3461474 | 0.65 | — | — | |
| SCHEMBL6466749 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842074-A1 | PROTEIN-DRUG CONJUGATES | Philogen S.p.A. (IT) | 2021-06-30 | — | — | EP | disclosed |
| US-10344079-B2 | Methods of treating a neoplastic disease | PHILOGEN S.P.A. (IT) | 2019-07-09 | — | — | US | disclosed |
| US-20160039920-A1 | Antibody-Drug Conjugates | PHILOCHEM AG (CH) | 2016-02-11 | — | — | US | disclosed |
| US-9198979-B2 | Thiazolidine linker for the conjugation of drugs to antibodies | PHILOGEN S.P.A. (IT) | 2015-12-01 | — | — | US | disclosed |
| US-20130309257-A1 | Thiazolidine Linker for the Conjugation of Drugs to Antibodies | PHILOGEN S.P.A. (IT) | 2013-11-21 | — | — | US | disclosed |
| EP-2621535-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | Philogen S.p.A. (IT) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041451-A1 | THIAZOLIDINE LINKER FOR THE CONJUGATION OF DRUGS TO ANTIBODIES | PHILOGEN S.P.A. (IT) | 2012-04-05 | — | — | WO | disclosed |