Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028110 | 1.00 | PIK3CD (0.61) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL10469223 | 1.00 | PIK3CD (0.61) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL2459843 | 1.00 | PIK3CD (0.61) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL4424510 | 0.91 | PIK3CD (0.52) | PIK3CDATMACEVHLMEN1 | |
| SCHEMBL17478617 | 0.89 | PIK3CD (0.60) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL17478614 | 0.89 | PIK3CD (0.60) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL17478603 | 0.89 | PIK3CD (0.60) | PIK3CDATMACEVHLCTSK | |
| SCHEMBL13804368 | 0.87 | PIK3CD (0.62) | PIK3CDATMVHLCTSKCHRNB2 | |
| SCHEMBL13862237 | 0.86 | ATM (0.54) | PIK3CDATMVHLMEN1KMT2A | |
| SCHEMBL4894931 | 0.86 | ATM (0.50) | PIK3CDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | disclosed |
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |
| EP-0486386-A2 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | disclosed |