Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | OXTR | P30559 | 2/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673883 | 1.00 | AVPR2 (0.51) | AVPR2AVPR1AOXTRAVPR1BHDAC1 | |
| SCHEMBL9028397 | 0.81 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9028332 | 0.81 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8670855 | 0.81 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9028386 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8670853 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9029202 | 0.80 | AVPR1A (0.63) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8672740 | 0.80 | AVPR1A (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9028728 | 0.80 | AVPR1A (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8677658 | 0.80 | AVPR1A (0.63) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |