Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.82 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.82 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.64 |
| ▸ | OXTR | P30559 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028478 | 1.00 | AVPR2 (0.82) | AVPR2AVPR1AAVPR1BOXTRABCB11 | |
| Hydrochloric Acid SCHEMBL9028914 | 0.91 | AVPR1A (0.84) | AVPR2AVPR1AAVPR1BOXTRABCB11 | |
| Hydrochloric Acid SCHEMBL9028922 | 0.91 | AVPR1A (0.84) | AVPR2AVPR1AAVPR1BOXTRABCB11 | |
| SCHEMBL7414955 | 0.90 | AVPR2 (1.00) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL7414954 | 0.90 | AVPR2 (1.00) | AVPR2AVPR1AAVPR1BOXTR | |
| Hydrochloric Acid SCHEMBL9029637 | 0.89 | AVPR2 (0.83) | AVPR2AVPR1AAVPR1BOXTRABCB11 | |
| Hydrochloric Acid SCHEMBL3503341 | 0.89 | AVPR2 (0.99) | AVPR2AVPR1AAVPR1BOXTR | |
| Hydrochloric Acid SCHEMBL3503338 | 0.89 | AVPR2 (0.99) | AVPR2AVPR1AAVPR1BOXTR | |
| Hydrochloric Acid SCHEMBL9029650 | 0.89 | AVPR2 (0.83) | AVPR2AVPR1AAVPR1BOXTRABCB11 | |
| Hydrochloric Acid SCHEMBL9028502 | 0.89 | AVPR2 (0.82) | AVPR2AVPR1AAVPR1BOXTRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |