Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169885 | 0.85 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL2169882 | 0.85 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL29674877 | 0.81 | HTT (0.66) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9028685 | 0.81 | MEN1 (0.58) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL3911774 | 0.81 | HTT (0.66) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL23142513 | 0.81 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL30767120 | 0.81 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL11313559 | 0.81 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| Bicarbonate SCHEMBL28506938 | 0.80 | MEN1 (0.54) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| Bicarbonate SCHEMBL29908570 | 0.80 | MEN1 (0.54) | MAPTALDH1A1SMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549943-B1 | Benzimidazole sulfonic acid derivatives as microbicides | CIBA GEIGY AG (CH) | 1996-05-22 | — | — | EP | disclosed |
| EP-0549943-A1 | Benzimidazole sulfonic acid derivatives as microbicides | CIBA-GEIGY AG (CH) | 1993-07-07 | — | — | EP | disclosed |