Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885397 | 0.95 | TACR2 (0.53) | TACR2TACR1HRH1 | |
| SCHEMBL9027580 | 0.92 | TACR2 (0.49) | TACR2TACR1HRH1 | |
| SCHEMBL9027911 | 0.90 | TACR2 (0.60) | TACR2TACR1 | |
| SCHEMBL9028189 | 0.90 | TACR2 (0.60) | TACR2TACR1 | |
| SCHEMBL8366587 | 0.90 | TACR2 (0.60) | TACR2TACR1 | |
| SCHEMBL9028237 | 0.90 | TACR2 (0.48) | TACR2TACR1HRH1 | |
| SCHEMBL9027989 | 0.90 | TACR2 (0.48) | TACR2TACR1HRH1 | |
| SCHEMBL9027765 | 0.90 | TACR2 (0.42) | TACR2TACR1POLB | |
| SCHEMBL9027216 | 0.89 | TACR2 (0.51) | TACR2TACR1 | |
| SCHEMBL9026804 | 0.89 | TACR2 (0.49) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |