Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180736 | 0.87 | HTT (0.70) | RXFP1HRH4HTTSIGMAR1HSD11B1 | |
| SCHEMBL31520498 | 0.87 | HTT (0.70) | RXFP1HRH4HTTSIGMAR1HSD11B1 | |
| SCHEMBL12845076 | 0.86 | RXFP1 (0.56) | RXFP1HRH4HTTSIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL5180774 | 0.85 | HTT (0.68) | RXFP1HRH4HTTSIGMAR1HSD11B1 | |
| SCHEMBL12569384 | 0.85 | HTT (0.67) | FNTAFNTBHTTHSD11B1LMNA | |
| SCHEMBL12569630 | 0.85 | HTT (0.72) | FNTAFNTBHTTHSD11B1LMNA | |
| SCHEMBL29432644 | 0.84 | HPGD (0.55) | RXFP1HRH4HTTSIGMAR1HSD11B1 | |
| SCHEMBL29816719 | 0.83 | HTT (0.65) | FNTAFNTBHTTLMNAKDM4E | |
| SCHEMBL8574260 | 0.82 | HTT (0.58) | FNTAFNTBHTTHSD11B1LMNA | |
| SCHEMBL14174296 | 0.82 | HTT (0.58) | HRH4FNTAFNTBHTTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703905-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-04-03 | — | — | EP | disclosed |