Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031083 | 0.88 | GRM5 (0.65) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9030318 | 0.80 | GRM5 (0.42) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29355216 | 0.78 | GRM5 (1.00) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL103061 | 0.78 | GRM5 (1.00) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL660360 | 0.76 | NPC1 (1.00) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL29394034 | 0.76 | NPC1 (1.00) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15470589 | 0.76 | CCR1 (0.60) | GRM5 | |
| SCHEMBL8854902 | 0.75 | MEN1 (0.55) | GRM5RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL8778633 | 0.74 | GRM5 (0.46) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8779683 | 0.73 | GRM5 (0.53) | GRM5NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557291-B1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | ZENECA LTD (GB) | 1996-08-14 | — | — | EP | disclosed |
| EP-0557291-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS. | ICI PLC (GB) | 1993-09-01 | — | — | EP | disclosed |
| US-5208239-A | Plant fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-04 | — | — | US | disclosed |
| WO-1992008714-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-29 | — | — | WO | disclosed |