Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044101 | 0.91 | KMT2A (0.36) | LSSNAMPTKMT2ACYP3A4TSHR | |
| SCHEMBL9030287 | 0.85 | KMT2A (0.39) | LSSNAMPTKMT2ACYP3A4EPHX2 | |
| SCHEMBL9030108 | 0.83 | NPC1 (0.38) | LSSNAMPTKMT2ACYP3A4TSHR | |
| SCHEMBL9030115 | 0.83 | NPC1 (0.38) | LSSNAMPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9387116 | 0.81 | KMT2A (0.32) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6132610 | 0.81 | LSS (0.42) | LSSNAMPTKMT2ACYP3A4TSHR | |
| SCHEMBL6044109 | 0.79 | KMT2A (0.36) | LSSKMT2ACYP3A4 | |
| SCHEMBL6132665 | 0.79 | HPGD (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9030305 | 0.78 | NPC1 (0.33) | NPC1 | |
| SCHEMBL6043237 | 0.77 | KMT2A (0.35) | LSSKMT2ACYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |