Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030576 | 1.00 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9029800 | 0.99 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9029791 | 0.99 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9030585 | 0.98 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9030189 | 0.90 | PPARA (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9030199 | 0.90 | PPARA (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9030571 | 0.90 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9029496 | 0.88 | PPARA (0.53) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9029482 | 0.88 | PPARA (0.53) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9028857 | 0.84 | MEN1 (0.47) | NPC1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535250-B1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0705817-A1 | New cannamide derivatives and their use as allergy inhibitors | TSUMURA & CO. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |