Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030856 | 1.00 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9031918 | 0.98 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9031912 | 0.98 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9714723 | 0.94 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9714732 | 0.94 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9821002 | 0.94 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9821009 | 0.94 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9031397 | 0.92 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9031400 | 0.92 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9031181 | 0.92 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397697-B1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RHONE POULENC RORER INT (US) | 1996-08-28 | — | — | EP | claimed |
| EP-0397697-A4 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1991-07-03 | — | — | EP | claimed |
| US-5028615-A | Treatment of hypersensitivity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-07-02 | — | — | US | claimed |
| EP-0397697-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4?. | RORER INT OVERSEAS (US) | 1990-11-22 | — | — | EP | claimed |
| US-4920130-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | RORER PHARAMCEUTICAL CORP. (US) | 1990-04-24 | — | — | US | claimed |
| WO-1989004304-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | claimed |