Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036571 | 0.89 | SLC29A1 (0.54) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| SCHEMBL9031407 | 0.86 | SLC29A1 (0.56) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| Hydrochloric Acid SCHEMBL10551361 | 0.85 | SLC29A1 (0.61) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| SCHEMBL9808176 | 0.82 | SLC29A1 (0.64) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| SCHEMBL10460559 | 0.82 | SLC29A1 (0.73) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| Water SCHEMBL10684017 | 0.82 | SLC29A1 (0.61) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| Hydrochloric Acid SCHEMBL9808242 | 0.82 | SLC29A1 (0.86) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| SCHEMBL10683605 | 0.81 | SLC29A1 (0.68) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| Hydrochloric Acid SCHEMBL7801696 | 0.81 | SLC29A1 (0.72) | SLC29A1KCNH2MEN1KMT2ASLC6A3 | |
| SCHEMBL10683035 | 0.80 | MEN1 (0.51) | SLC29A1KCNH2MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727421-A1 | Agents for improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-21 | — | — | EP | disclosed |
| US-5026853-A | Sleep and cardiovascular disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-06-25 | — | — | US | disclosed |
| US-4968684-A | N-ARYL-PIPERAZINEALKANAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-06 | — | — | US | disclosed |
| US-4880808-A | SEDATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-11-14 | — | — | US | disclosed |
| EP-0285219-A2 | Method of improving sleep | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-10-05 | — | — | EP | disclosed |