Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.81 |
| ▸ | HMGCR | P04035 | 5/20 | 0.77 |
| ▸ | RXRA | P19793 | 3/20 | 0.77 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13403184 | 1.00 | NR4A2 (0.81) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL14273651 | 1.00 | NR4A2 (0.81) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL14262699 | 1.00 | NR4A2 (0.81) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL13776435 | 0.92 | NR4A2 (0.81) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL14569976 | 0.90 | NR4A2 (0.87) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL10049193 | 0.90 | NR4A2 (0.87) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL14569977 | 0.90 | NR4A2 (0.87) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| SCHEMBL12058587 | 0.90 | NR4A2 (0.80) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| Pitavastatin SCHEMBL10049191 | 0.90 | PDE4D (1.00) | NR4A2PDE4DNR1I2HMGCRRXRA | |
| Pitavastatin SCHEMBL3369 | 0.90 | PDE4D (1.00) | NR4A2PDE4DNR1I2HMGCRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339062-B2 | Method for producing a 3,5-dihydroxy-6-heptenoate | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-03-04 | — | — | US | disclosed |
| EP-0742209-A2 | A process for producing an optically active quinolinemevalonolactone and a process for producing an optically active quinolinemevalonic acid salt | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5514804-A | DEHYDRATION AND ESTERIFICATION WITH CYCLIZATION AND SALT FORMATION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5473075-A | Optical resolution after forming amine salt, separating; intermediate | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| US-5284953-A | Treatment and prevention of hyperlipemia and arteriosclerosis | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-02-08 | — | — | US | disclosed |