Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032686 | 0.99 | HRH3 (0.41) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9032671 | 0.86 | HRH3 (0.42) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9033916 | 0.85 | HRH3 (0.40) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9033194 | 0.85 | HRH3 (0.45) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL8697759 | 0.85 | HRH3 (0.45) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9032167 | 0.84 | HRH3 (0.44) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9034996 | 0.83 | HRH3 (0.43) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9034551 | 0.81 | HRH3 (0.39) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL8697765 | 0.80 | HRH3 (0.43) | HRH3KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL9033054 | 0.80 | HRH3 (0.44) | HRH3KDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |