Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030883 | 0.85 | ACE (0.33) | ALDH1A1USP2GAAS1PR3 | |
| SCHEMBL9030932 | 0.85 | ACE (0.33) | ALDH1A1USP2GAAS1PR3 | |
| SCHEMBL9032401 | 0.85 | ACE (0.33) | ALDH1A1USP2GAAS1PR3 | |
| SCHEMBL9032621 | 0.85 | ACE (0.33) | ALDH1A1USP2GAAS1PR3 | |
| SCHEMBL9032393 | 0.85 | ACE (0.33) | ALDH1A1USP2GAAS1PR3 | |
| SCHEMBL9032282 | 0.80 | HRH3 (0.32) | — | |
| SCHEMBL9033143 | 0.74 | USP2 (0.31) | ALDH1A1USP2GAA | |
| SCHEMBL9032355 | 0.73 | USP2 (0.30) | ALDH1A1USP2GAA | |
| SCHEMBL9032350 | 0.73 | USP2 (0.30) | ALDH1A1USP2GAA | |
| SCHEMBL9033457 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558287-B1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5292767-A | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0558287-A1 | Tetrahydrothiophene derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |