⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260079 | 0.71 | — | — | |
| SCHEMBL27301656 | 0.71 | — | — | |
| Phosphine SCHEMBL27619357 | 0.71 | — | — | |
| SCHEMBL39371 | 0.71 | — | — | |
| SCHEMBL28735038 | 0.71 | — | — | |
| Selenium SCHEMBL29353915 | 0.71 | — | — | |
| SCHEMBL25435588 | 0.50 | — | — | |
| SCHEMBL22614697 | 0.50 | — | — | |
| SCHEMBL20541415 | 0.50 | — | — | |
| Lithium Ion SCHEMBL20603256 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805322-B | Prins reaction and intermediate for synthesizing halichondrin macrolides and analogues thereof | 卫材R&D管理有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-118894868-A | Prins reactions and compounds useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-111868044-B | Prins reactions and compounds useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-114805322-A | Prins reactions and intermediates useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-109641917-B | Prins reactions and intermediates useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-113735896-A | Method for preparing Z-configuration-1, 2-di-tin substituted olefin by adopting monoatomic palladium-phosphine ligand | 广西师范大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-111868044-A | Prins reaction and compounds useful for the synthesis of halichondrin macrolides and analogs thereof | 卫材R&D管理有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-9578729-B2 | Extreme ultraviolet source with dual magnetic cusp particle catchers | PLEX LLC (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160150625-A1 | EXTREME ULTRAVIOLET SOURCE WITH DUAL MAGNETIC CUSP PARTICLE CATCHERS | PLEX LLC (US) | 2016-05-26 | — | — | US | disclosed |
| CN-1107678-C | Highly lipophilic camptothecin derivatives, preparation method and uses thereof | BIONUMERIK PHARMACEUTICALS INC (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1052238-C | Conception promoting 19, 11beta-overbrige 4-estratrene | SCHERLING AG (DE) | 2000-05-10 | — | — | CN | disclosed |
| CN-1227559-A | Highly lipophilic camptothecin derivatives | BIONUMERIK PHARMACEUTICALS INC (US) | 1999-09-01 | — | — | CN | disclosed |
| EP-0486806-B1 | Process for the preparation of racemic pilosinine derivatives | MERCK PATENT GMBH (DE) | 1996-01-17 | — | — | EP | disclosed |
| CN-1092428-A | 19 of gestagen effect is arranged, the female alkene that 11-builds bridge | SCHERING AG (DE) | 1994-09-21 | — | — | CN | disclosed |
| EP-0486806-A1 | Process for the preparation of racemic pilosinine derivatives | MERCK PATENT GmbH (DE) | 1992-05-27 | — | — | EP | disclosed |