Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035792 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9034270 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7217901 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7310391 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9034692 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9035433 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9036366 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9035995 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9034865 | 1.00 | SETD7 (1.00) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7213774 | 0.99 | SETD7 (0.97) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |